SOCIAL MEDIA

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Sandra Ortiz-Cuaran EGFR, NSCLC, AACR21: 11/04/2021 18:32:00


Mechanisms of resistance to combined osimertinib and savolitinib in #EGFR-mutant #NSCLC (TATTON trial), presented by A. Markovets @AACR #AACR21. ctDNA profiling revealed acquired -mainly compound- MET mutations. Genomic alterations in EGFR, KRAS and PIK3CA were also observed.


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Nature Medicine Tcell, lungcancer, immunotherapy, NSCLC, TRACERx, AACR21: 11/04/2021 14:52:29


@CharlesSwanton @NickyMcGranahan A survey of #Tcell repertoire evolution in patients with early-stage untreated #lungcancer offers an opportunity to monitor and identify neoantigen-specific T cells for personalized #immunotherapy @BennyChain @QuezadaLab #NSCLC #TRACERx #AACR21


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Elizabeth McKenna KRAS, G12C, AACR21: 11/04/2021 13:30:00


Early results showed #KRAS #G12C inhibitors were less active in CRC than NSCLC; a 2020 @CD_AACR paper by @Sandra_Misale @Albert0Bardelli et al suggested that the lower responses might be due to EGFR, a la what had been seen with BRAF inhibitors /4 #AACR21


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filippo masini : 11/04/2021 14:01:28


Detection of Low-Frequency KRAS Mutations in cfDNA From EGFR-Mutated NSCLC Patients After First-Line EGFR Tyrosine Kinase Inhibitors


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Targeted Oncology LCSM: 11/04/2021 14:01:33


Earlier diagnosis and biomarker testing should be more widely implemented to identify patients with EGFR-positive non–small lung cancer who may benefit for EGFR inhibition. #LCSM


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filippo masini : 11/04/2021 14:03:04


Optimizing the sequencing of tyrosine kinase inhibitors (TKIs) in epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC)


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Xiuning Le MD PhD : 11/04/2021 14:55:28


Nice to see a meaningful toxicity reduction. @Exon20Group @EGFRResisters Safety of Twice-Daily Poziotinib in EGFR- or HER2 Exon 20–Positive NSCLC


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Targeted Oncology LCSM: 11/04/2021 16:01:19


Xiuning Le, MD, PhD, discusses the limited treatment options available for patients with non–small cell lung cancer and an EGFR exon 20 mutation. #LCSM


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Eric Thompson : 12/04/2021 00:12:23


Level of chromosomal abnormality in lung cancer may predict immunotherapy response -


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